Ashton Kutcher's ex-wife, Demi Moore, appears in the opening monologue.
Cameron Diaz makes a guest appearance in "The Cougar Den" sketch.
Gnarls Barkley performed "Run (I'm a Natural Disaster)" and "Who's Gonna Save My Soul".
Casey Wilson's "paralyzed stripper" sketch was one of the pieces she performed in her SNL audition.
The three-part pre-taped sketch "Death By Chocolate" (where a walking candy bar [Ashton Kutcher] kills people in gruesome ways) was directed by Jason Reitman (director of Juno and Thank You for Smoking).
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