Justin Timberlake won an Emmy for hosting this episode.
Susan Sarandon and Patricia Clarkson made guest appearances during the Digital Short.
Ciara performed "Love Sex Magic" with Justin Timberlake and "Never Ever". Jessica Biel introduced "Love Sex Magic."
Chris Pine, Zachary Quinto and Leonard Nimoy cameo-ed on Weekend Update in a commentary on Star Trek.
Jimmy Fallon reprised his role as Barry Gibb for another installment of "The Barry Gibb Talk Show".
Darrell Hammond does not appear in this episode.
In dress rehearsal Rachel Dratch reprised her Debbie Downer character on Weekend Update giving a commentary on the Swine Flu outbreak.
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