Usher performed "Scream" and "Climax" and appeared in the SNL Digital Short and the "2012 Funkytown Debate" sketch.
Will Ferrell reprised his impression of George W. Bush in the cold open. Ferrell's mother, Betty Kay Ferrell, appeared in the opening monologue.
Ana Gasteyer reprised her role as Bobbi Mohan-Culp in the LGBT Prom sketch. Will Forte reprised his role as Greg Stink in the ESPN Classic sketch and his role as Hamilton in the "25th Anniversary Celebration" sketch.
Justin Bieber, Jorma Taccone, Julian Casablancas, Jon Hamm, Justin Timberlake, Natalie Portman, Michael Bolton, and Akiva Schaffer appeared in the 100th SNL Digital Short.
Liam Neeson appeared on Weekend Update to promote the 2012 movie Battleship. Will Ferrell's third time hosting.
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