After Melissa Conner performs what should be a straightforward surgery on firefighter Renee Hudson, Renee is left in mysterious and agonizing pain. As Mel and Jerry retrace their medical steps trying to find the cause, the cracks in their relationship are exposed. Allen's first day in ER is complicated by the strange and violent behavior of Tyson “Pitbull” Danko, and Allen and Cutler need to work together in order to keep Pitbull in hospital long enough to find out what‟s really wrong with him. Griffin and Zoe pull together to help a still-reeling Kanaskie eradicate a bedbug problem at Beth-H.
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