Gary Lineker introduces highlights of the evening's Premier League action in a special midweek edition of Match of the Day.
The Manchester derby is always a passionate affair, but with both United and City both genuine Premier League title contenders, the match at the City of Manchester Stadium promises to be a fascinating encounter.
There's another derby in West London, where Chelsea host a Fulham side now managed by former Stamford Bridge favourite Mark Hughes. Blackpool travel to Aston Villa for their first top-flight clash since 1967, and Blackburn boss Sam Allardyce returns to Newcastle, where he spent an unhappy eight months in charge in 2007.
Elsewhere, struggling West Ham host Roberto Di Matteo's West Bromwich Albion, Bolton travel to Everton and Wolves host Arsenal. The programme will also feature highlights of Tuesday's games between Stoke and Birmingham, and Tottenham versus Sunderland.
Stoke City v Birmingham City Tottenham v Sunderland Newcastle v Blackburn Rovers Chelsea v Fulham Aston Villa v Blackpool Wolves v Arsenal Wigan v Liverpool West Ham v West Brom Manchester City v Manchester United Everton v Bolton
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