The changes in the western frontier take their toll on the Native people. Some choose to cast their lot with the white man, while others cling to their traditional ways. Jacob Wheeler and his wife, Thunder Heart Woman, return to Virginia, but soon the promise of a new life in California entices Jacob to set out again along with his brother Jethro. The road is long and hard. Many are lost, and in the end, one brother makes the ultimate sacrifice.
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