Medavoy and Martinez work a strangulation murder case that appears to be the work of a cross-dresser. Andy has a bad tooth, hates needles, and tries to prevent a dentist from jumping off a 28th floor ledge; he fails. LaSalle's first case involves a woman who was raped and she, John, Andy, Janice and Licalsi's hot-headed new partner try to catch the most probable suspect; however the hot-head blows the bust. Lois tries to reconcile her relationship with Andy.
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