A murder scene complete with lots of blood but no victim and high tech life-extension science are all part of the investigation as Castle and Beckett try to solve a murder without a body. Meanwhile, Alexis waits to hear news about her application to Stanford
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Gunshots, a fleeing van and a massive blood pool all point to murder, but when Castle & Beckett arrive at the crime scene, they discover that it lacks something - the victim! The investigation leads to the cutting-edge world of life-extension science, a cunning high-tech researcher, and a sleazy porn mogul who invested in a modern-day "fountain of youth." Meanwhile, Alexis finds out whether she got into Stanford.