Starting with this episode, Seth Meyers is the new Weekend Update anchor with Amy Poehler, which also includes a cameo appearance by Brian Williams.
This is the first episode featuring new director, Don Roy King.
This episode has a different representation of the Saturday Night Live logo and how the host and musical guests appear in the opening credits than what's depicted in the next episode.
Lenny Pickett, Earl Gardner, and Steve Turre accompanied the Killers as the horn section during their 2nd song, "Bones."
The Killers Performed "When You Were Young" and "Bones."
NBC reaired this episode just 2 weeks later, at the time, the shortest span of time between an episode and its repeat (until the Jon Hamm/Coldplay episode in season 34, which aired on primetime Saturday night the week after it premiered).
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